Adjunctive Therapy of Gastric Cancer: Moving the Field Forward.

Despite a decrease in incidence, gastric cancer continues to be the third leading cause of cancer-related death worldwide.[1] For localized disease, surgery offers the best chance for cure. Despite surgery with curative intent, however, many patients experience recurrences, leading to dismal outcomes. With the goal of improving survival, neoadjuvant and adjuvant therapies have emerged. However, there are significant differences between countries and regions with regard to the management of localized gastric cancer. Dr. Chan and colleagues have provided an instructive article outlining current strategies used in the treatment of localized gastric cancer.[2] We should emphasize that for appropriate staging, a complete evaluation with computed tomography imaging, endoscopy with endoscopic ultrasound, and staging laparoscopy is recommended in all patients with localized disease.[3,4]